Irf3 molecular weight

Author: jdxh

August undefined, 2024

WebJul 7, 2024 · Phospho-S365 acts as a docking site for IRF3, a transcription factor that is phosphorylated and activated by TBK1, leading to transcriptional induction of type I interferons (IFNs). Type I IFNs... IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 is found …

Sowmya Pattabhi - Director Correlative Sciences …

WebMolar mass of IrF3 = 249.2122096 g/mol This compound is also known as Iridium (III) Fluoride. Convert grams IrF3 to moles or moles IrF3 to grams Molecular weight calculation: 192.217 + 18.9984032*3 Percent composition by element Similar chemical formulas Note that all formulas are case-sensitive. WebMar 10, 2011 · Regardless of this technical point, the clear presence of a high molecular weight band demonstrates that PU.1 is an additional DNA binding factor at the IFN-β … dhl how to send a package

IRF-3 (D83B9) Rabbit mAb Cell Signaling Technology

WebDetects a band of approximately 55 kDa (predicted molecular weight: 47 kDa). Flow Cyt Use 1µg for 10 6 cells. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Target. Function. ... Anti-IRF3 antibody [IRF35I218] (ab50772) was used in Chen GY et al. Baculovirus transduction of mesenchymal stem ... WebMolar mass of IrF3 = 249.2122096 g/mol Convert grams Iridium (III) Fluoride to moles or moles Iridium (III) Fluoride to grams Molecular weight calculation: 192.217 + … WebInterferon regulatory factor 3 (Human) UniProt Q14653 - IRF3_HUMAN Gene IRF3 Modification Unmodified Visit Supplier Website Request a Quote from Santa Cruz Biotechnology Supplier provided information Validations None provided Applications None provided Reactivity Homo sapiens (Human) Mus musculus (House mouse) Rattus … dhl hts code

IRF8 and IRF3 cooperatively regulate rapid interferon-β induction …

IKKε and TBK1 are essential components of the IRF3 signaling

WebPhosphorylated IRF3 dissociates from the adapter proteins, dimerizes, and then enters the nucleus to induce IFNs ( PubMed: 25636800, PubMed: 27302953 ). 3 publications 3 … WebNov 6, 2024 · Myocardial infarction (MI) elicits inflammation 5, but the dominant molecular drivers of MI-associated inflammation remain unclear. Here we show that ischemic cell death and uptake of cell debris ... ci investments fund code 432WebMay 31, 2024 · Additionally, we also confirmed that treatment with intracellular (IC) poly (I:C) (low molecular weight), a ligand of DDX58, could also lead to a concentration-dependent reduction of the protein level of IRF3 at the late stage (24 h) post-poly (I:C) ... Lysates of IRF3 KO 293 T cells transfected with the ISRE luciferase reporter, ... dhl hr team

"WebKey features and details Rabbit polyclonal to IRF3 (phospho S396) Suitable for: WB Reacts with: Human Isotype: IgG You may also be interested in Primary Anti-IRF3 (phospho S386) antibody [EPR2346] - BSA and Azide free (ab182859) Protein Recombinant Human IRF3 protein (ab205216) Secondary Goat Anti-Rabbit IgG H&L (HRP) (ab205718) " - Irf3 molecular weight

Irf3 molecular weight

IRF-3 (D83B9) Rabbit mAb Cell Signaling Technology

WebJan 4, 2024 · To determine the molecular mechanism by which UAP1 promotes type I IFN signaling, ... (20 mg/kg body weight [BW]) ... Total lysates were prepared from IRF3 KO HEK293T cells transfected with Flag-IRF3 and followed by immunoprecipitation with α-Flag M2 beads. Immunoprecipitated proteins were separated by SDS-PAGE, and then stained … http://www.endmemo.com/chem/compound/fef3.php

Did you know?

WebKey component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. WebShowing 1-11 of 11 results for "irf3 inhibitor" within Products. Products Genes Papers Technical Documents Site Content Chromatograms. Filter & Sort. All Photos (1) BX-795. ...

WebApr 29, 2024 · Once the cross flow was applied (Figure 3b, overlapping orange, blue and green graphs) cGAMP recovery was 61.7% (1.9 ± 0.2 μg recovered), probably due to losses through the membrane with a high molecular weight cut off (10 kDa), with respect to the molecular weight of cGAMP (718.28 g/mol) . UV was thus used for further studies on … WebAug 16, 2024 · This is essential for STING polymerization and TBK1-mediated STING and IRF3 phosphorylation. ... effects on transcription of downstream antiviral genes induced by transfected low-molecular weight ...

WebFeb 26, 2024 · Nsp12 did not impair IRF3 phosphorylation but suppressed the nuclear translocation of IRF3. ... After 24 h, the cells were stimulated with SeV or high-molecular weight poly(I:C) (HMW-poly[I:C]), ... WebSynthetic peptide corresponding to Human IRF3 (phospho S386). Database link: Q14653 Positive control WB: MCF7 cells treated with Calyculin A. General notes This product is a …

WebIRF-3 is expressed ubiquitously as an inactive monomer in the cytosol. When cells are stimulated with poly (I:C) or virus infection, serine residues in the C-terminal region of IRF …

WebMAVS and IRF3 form a ubiquitination- and phosphorylation-dependent complex 442 MAVS 4T/S site, including Ser, is phosphorylated redundantly by TBK1 and IKK IRF3 C terminus harbors positively charged surfaces important for MAVS-IRF3 interaction and IRF3 dimerization Materials and methods Innate immune receptor signaling, united ci investments greg giffinWebNational Center for Biotechnology Information ci investments calgaryWebMar 10, 2011 · Regardless of this technical point, the clear presence of a high molecular weight band demonstrates that PU.1 is an additional DNA binding factor at the IFN-β promoter. ... IRF8 cooperates with IRF3 to regulate IFN-β transcription. (A) The genomic sequence of human IFN-β from −79 bp to −58 bp. The IRF3- and IRF8-binding sites are … dhl hub accentureWebProduct Specific Information This antibody detects endogenous protein at a molecular weight of 47 and 55 kDa. Purity is >95% by SDS-PAGE. Target Information IFR3 (interferon regulatory factor 3) is a key transcriptional … ci investments high income fundWebIrF3 molecular weight Molar mass of IrF3 = 249.2122096 g/mol This compound is also known as Iridium (III) Fluoride. Convert grams IrF3 to moles or moles IrF3 to grams … ci investments chairman bill hollandWebDec 18, 2015 · The native protein migrates at 50kDa, but the predicted molecular weight of the mature protein is 28.9. Antigenically active … dhl how to send a parcelWebAug 10, 2024 · Introduction. Interferon regulatory factor 9 (IRF9) was first discovered as part of a protein subunit purified from the interferon-stimulated gene factor 3 (ISGF3) complex ().Early studies have referred IRF9 as ISGF3γ and p48—due to its molecular weight of 48 kDa (1–4).IRF9 is best characterized as a transcription factor that mediates (as part … dhl hub colnbrook