WebApr 5, 2024 · INDICATIONS. Diazepam rectal gel is a gel formulation of diazepam intended for rectal administration in the management of selected, refractory, patients with epilepsy, on stable regimens of AEDs, who require intermittent use of diazepam to control bouts of increased seizure activity.. Evidence to support the use of diazepam rectal gel … WebSep 3, 2024 · Administration. Diazepam is available in multiple formulations, including oral tablets, intramuscular injections (IM), intravenous injections (IV), or rectal gel. Oral …
Diazepam Rectal: MedlinePlus Drug Information
WebDiazepam is metabolized in the liver with only traces of the unchanged drug excreted in urine. A very small proportion of the metabolites is excreted through the bile into the intestine and eliminated with the feces. After rectal administration in suppository form diazepam is significantly absorbed and peak concentration reaches within 1.5-2 hours. gloucester stationery
How and when to take diazepam - NHS
Diazepamis a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Diazepam rectal (for use in the rectum) is used to treat occasionally increased seizures (cluster seizures) in people with epilepsywho also take other seizure medicines. Diazepam rectal is not for long-term daily use to prevent seizures. Diazepam rectal may also … See more Diazepam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. MISUSE OF diazepam rectal CAN CAUSE ADDICTION, … See more You should not use this medicine if you are allergic to diazepam (Valium). You may not be able to use diazepam rectal if you have glaucoma. … See more Diazepam rectal is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time. See more Follow the directions on your prescription label and read all medication guides or instruction sheets. Never use diazepam in larger amounts, or … See more WebVaginal administration of diazepam results in lower peak serum plasma concentration, longer time to peak concentration, and lower bioavailability than standard oral use. … Web11. Knudsen FU. Rectal administration of diazepam in solution in the acute treatment of convulsions in infants and children. Arch Dis Child. 1979;54(11):855- 857. 12. Milligan NM, et al. A clinical trial of single dose rectal and oral administration of diazepam for the prevention of serial seizures in adult epileptic patients. boilermakers california