WebMar 15, 2024 · As the scoring method, maximum clique centrality (MCC) was selected to identify featured nodes. In the cytoHubba plugin, the MCC algorithm has been reported … WebDec 5, 2024 · Hub genes were identified using the cytoHubba Cytoscape plugin, and maximal clique centrality (MCC) was identified. The MCODE Cytoscape plugin was used to identify network clusters, or highly interconnected regions. RESULTS There were 586 and 392 DEGs identified from the GSE103176 and GSE54644 datasets, respectively.
Cytoscape App Store - cytoHubba
WebJul 2, 2024 · (B) Top 10 hub genes calculated by the MCC method in CytoHubba software. The gradation of color represents the value of the score according to the MCC method, and the VEGFA score was the … WebSYK, CBL, VAV1, LCK, and CD3G genes were identified as hubs by both methods. The analytic score for these top thirty hub genes was obtained through ranking by the MCC … clearly offers
4. Quick Tour of Cytoscape - Cytoscape 3.9.1 User Manual
WebFeb 10, 2024 · The maximal clique centrality (MCC) method screened the hub genes. Survival analysis Gene expression profiling interactive analysis (GEPIA) ( http://gepia.cancer-pku.cn) allows users to interact with … WebApr 11, 2024 · To identify functional clusters of genes in the PPI network, Molecular Complex Detection (MCODE) in Cytoscape was used, with a degree cutoff of 2, node score cutoff of 0.2, k-core of 2, and maximum depth of 100 [ 23 ]. Modules with proven scores greater than 5 were eliminated. WebMay 12, 2024 · A protein-protein interaction (PPI) network was constructed using Cytoscape v3.7.0. The hub genes were selected using the Maximal Clique Centrality (MCC) method. A circRNA-miRNA-hubgene (ceRNA) network was constructed using Cytoscape v3.7.0. Results CircRNA expression profile in plasma of OC and control patients blue ridge institute nih funding